This issue's cover uses a transparent model of a laboratory scientist to depict some of the neural pathways involved in transforming sensory input into motor action. In our example, the scientist must use visual information to guide his hand and arm to place solution into the correct vial. Such a task is easily performed by a human but is beyond the abilities of even the most sophisticated robot. The articles in this issue of the Barrow Quarterly describe research programs designed to understand how we sense the world, transmit and process sensory information along neural pathways, and ultimately use that information to produce movement. The illustration is by Mark Schornak and Michael Hickman.