This issue's cover depicts three stages in the life of the brain of an Alzheimer's patient, from growth and development in infancy to atrophy in old age.  The images at the top represent common micropathological features of Alzheimer's disease: amyloid plaques and neurofibrillary tangles. This issue of the Barrow Quarterly is dedicated to articles on Alzheimer's disease and other dementias. The illustration is by Mark Schornak.