Andrew S. Little, MD
Andrew S. Little, MD
Director, Neurological Intensive Care Unit
Director, Barrow Pituitary Outcomes Project
Dr. Andrew Little specializes in the treatment of pituitary tumors and other lesions of the skull base. He uses minimally invasive surgery and endoscopic endonasal techniques to improve patient comfort. He also treats nonpituitary brain tumors and performs complex spinal surgery.
After graduating magna cum laude from Yale University with a degree in Biochemistry and Biophysics, Dr. Little worked as a research scientist for a biotech company in California. Fascinated by the clinical application of his research, he was inspired to pursue a career in medicine.
Dr. Little went on to earn his medical degree at the University of California-Irvine and complete his neurosurgical residency at Barrow Neurological Institute. Dr. Little trained as a fellow under the guidance of Charles Teo, MD, in Sydney, Australia (minimally invasive surgery and neuroendoscopy) and under Volker K. H. Sonntag, MD, at Barrow (spinal neurosurgery). He has published numerous peer-reviewed medical articles and his research focuses on minimally invasive surgery.
Selected Professional Memberships and Appointments
- Director, Barrow Pituitary Outcomes Project
- Director, Intensive Care Unit, Barrow Neurological Institute
- Congress of Neurological Surgeons
- American Association of Neurological Surgeons
- Ad hoc reviewer, Neurosurgery, Child’s Nervous System
Education, Training, and Previous Positions
- 2008-2009: Fellowship, Minimally Invasive and Endoscopic Neurosurgery, Prince of Wales Private Hospital, Sydney, Australia
- 2007-2008: Fellowship, Complex Spine Surgery, Barrow Neurological Institute
- 2003-2010: Neurosurgical Residency, Barrow Neurological Institute
- 2003: MD, University of California - Irvine College of Medicine
- 1995: BS, Yale University, Biochemistry and Biophysics
Selected Honors and Awards
- John Green Award, Arizona Neurosurgical Society
- Alpha Omega Alpha Honor Medical Society, University of California - Irvine College of Medicine
- Magna cum Laude, Yale University
- Honors in Major, Yale University
Little AS, White WL. Short-duration, single-agent antibiotic prophylaxis for meningitis in trans-sphenoidal surgery. Pituitary. Feb 24 2011.
- Wait SD, Garrett MP, Little AS, Killory BD, White WL. Endocrinopathy, vision, headache, and recurrence after transsphenoidal surgery for Rathke cleft cysts. Neurosurgery. Sep 2010;67(3):837-843; discussion 843.
Little AS, Zabramski JM, Nakaji P. Simplified aqueductal stenting for isolated fourth ventricle using a small-caliber flexible endoscope in a patient with neurococcidiomycosis: technical case report. Neurosurgery. Jun 2010;66(6 Suppl Operative):373-374; discussion 374.
Little AS, White WL. Prophylactic antibiotic trends in transsphenoidal surgery for pituitary lesions. Pituitary. Aug 31 2010.
Little AS, Liu S, Beeman S, Sankar T, Preul MC, Hu LS, Smith KA, Baxter LC. Brain retraction and thickness of cerebral neocortex: an automated technique for detecting retraction-induced anatomic changes using magnetic resonance imaging. Neurosurgery. Sep 2010;67(3 Suppl Operative):ons277-282; discussion ons282.
Little AS, Smith KA, Kirlin K, Baxter LC, Chung S, Maganti R, Treiman DM. Modifications to the subtemporal selective amygdalohippocampectomy using a minimal-access technique: seizure and neuropsychological outcomes. J Neurosurg. Dec 2009;111(6):1263-1274.
Little AS, Shetter AG, Shetter ME, Kakarla UK, Rogers CL. Salvage gamma knife stereotactic radiosurgery for surgically refractory trigeminal neuralgia. Int J Radiat Oncol Biol Phys. Jun 1 2009;74(2):522-527.
Little AS, Shetter AG, Shetter ME, Bay C, Rogers CL. Long-term pain response and quality of life in patients with typical trigeminal neuralgia treated with gamma knife stereotactic radiosurgery. Neurosurgery. Nov 2008;63(5):915-923; discussion 923-914.
Little AS, Jittapiromsak P, Crawford NR, Deshmukh P, Preul MC, Spetzler RF, Bambakidis NC. Quantitative analysis of exposure of staged orbitozygomatic and retrosigmoid craniotomies for lesions of the clivus with supratentorial extension. Neurosurgery. May 2008;62(5 Suppl 2):ONS318-323; discussion ONS323-314.